This introduction to the special issue of AJMG Part C: Overgrowth Syndromes updates the current understanding of overgrowth syndromes. We clarify the terminology associated with overgrowth, review some common pathways to overgrowth and present a preliminary classification based on currently known genomic and epigenetic mechanisms. We introduce the articles of this issue—new research and reviews of well-established and recently described overgrowth syndromes of the brain, body or both.
|Original language||English (US)|
|Number of pages||8|
|Journal||American Journal of Medical Genetics - Seminars in Medical Genetics|
|State||Published - Dec 1 2019|
- epigenetic regulation
PubMed: MeSH publication types
- Journal Article