TY - GEN
T1 - Arabidopsis defense response against pseudomonas syringae - Effects of major regulatory genes and the impact of coronatine
AU - Wang, Lin
AU - Katagiri, Fumiaki
AU - Glazebrook, Jane
PY - 2009
Y1 - 2009
N2 - Arabidopsis defense response against the bacterial pathogen, Pseudomonas syringae, is a complex and highly regulated process. Previous studies have identi-fied many critical genes encoding regulators that govern innate immunity, but comprehensive transcriptome analysis of corresponding mutants is lacking. Using a custom microarray, we profiled the transcriptome of many mutants with mutations in critical regulatory genes affecting Arabidopsis disease resistance. We show that previously identified mutants affecting the salicylic acid (SA) sector of the defense network have similar tran-scriptional profiles. Surprisingly, jin1, jar1 and dde2 that are involved in jasmonates (JA) sector did not show ma-jor transcriptome changes, while coi1 did. Further analy-sis revealed that the phytotoxin, coronatine, secreted by P. syringae, is responsible for nearly all COI1-mediated responses.
AB - Arabidopsis defense response against the bacterial pathogen, Pseudomonas syringae, is a complex and highly regulated process. Previous studies have identi-fied many critical genes encoding regulators that govern innate immunity, but comprehensive transcriptome analysis of corresponding mutants is lacking. Using a custom microarray, we profiled the transcriptome of many mutants with mutations in critical regulatory genes affecting Arabidopsis disease resistance. We show that previously identified mutants affecting the salicylic acid (SA) sector of the defense network have similar tran-scriptional profiles. Surprisingly, jin1, jar1 and dde2 that are involved in jasmonates (JA) sector did not show ma-jor transcriptome changes, while coi1 did. Further analy-sis revealed that the phytotoxin, coronatine, secreted by P. syringae, is responsible for nearly all COI1-mediated responses.
UR - http://www.scopus.com/inward/record.url?scp=70349506998&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349506998&partnerID=8YFLogxK
U2 - 10.1109/GENSIPS.2009.5174327
DO - 10.1109/GENSIPS.2009.5174327
M3 - Conference contribution
AN - SCOPUS:70349506998
SN - 9781424447619
T3 - 2009 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2009
BT - 2009 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2009
T2 - 2009 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2009
Y2 - 17 May 2009 through 21 May 2009
ER -