Are Large Nonfunctional Kidneys Risk Factors for Posttransplantation Urinary Tract Infection in Patients With End-Stage Renal Disease Due To Autosomal Dominant Polycystic Kidney Disease?

M. Salehipour, H. Jalaeian, H. Salahi, A. Bahador, H. R. Davari, S. Nikeghbalian, M. M. Sagheb, G. A. Raiss-Jalali, J. Roozbeh, S. Behzadi, P. Janghorban, H. N. Sepas, S. A. Malek-Hosseini

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5 Scopus citations

Abstract

Objectives: The objective of this study was to evaluate the effect of bilateral nephrectomy on posttransplantation urinary tract infection (UTI) among patients with end-stage renal disease (ESRD) due to autosomal dominant polycystic kidney disease (ADPKD). Methods: In a retrospective case-control design, 62 patients with ESRD with ADPKD were divided into 2 groups: (A) 24 patients who underwent bilateral nephrectomies, and (B) 38 patients in whom bilateral nephrectomies had not been done. Pretransplantation and posttransplantation urine cultures were evaluated for UTI. Results: Sixty-two patients with ESRD with ADPKD were enrolled in this study. The average age was 42 years (range, 6-60 years). Forty patients (64.5%) were male and 22 (35.5%) were female. The mean duration of hemodialysis was 24 months (range, 2-120 months), which was the same for both groups. Bilateral nephrectomies were done for 24 participants (38.7%). There were 38 patients (61.3%) in group B who did not have the operation. UTI occurred in 23 patients (37.1%): 6 patients (25%) in group A and 17 patients (44.7%) in group B. The incidence of UTI was not statistically different between the 2 groups (P > .05). Furthermore, no relationship was found between age, gender, blood group, and UTI in patients with ADPKD (P > .05). Conclusion: According to our study, the presence of large nonfunctional kidneys is not a risk factor for posttransplantation UTI in patients with ADPKD and ESRD.

Original languageEnglish (US)
Pages (from-to)887-888
Number of pages2
JournalTransplantation proceedings
Volume39
Issue number4
DOIs
StatePublished - May 1 2007

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