Association of a common D3 dopamine receptor gene variant is associated with sensation seeking in skiers and snowboarders

Cynthia J. Thomson, Scott R. Carlson, Jim L. Rupert

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The 'sensation seeking' trait has been associated with risky behaviors including high-risk sport participation. Genes involved in dopaminergic neurotransmission have been investigated in studies of approach traits; however, not in sporting contexts. We used joint-analysis to investigate the relationship between monoamine-neurotransmitter gene variants and impulsive and sport-specific sensation seeking in skiers (n= 599). An initial screen identified a few variants that were associated with sensation seeking, one of which, a G/A transition (rs167771) in the D3-receptor gene (DRD3), remained significant in the combined sample and after correction for multiple testing (p= .004, ηp2=.02). DRD3 variants have been associated with approach traits; however, our results are the first to suggest a role for rs167771 in sensation seeking.

Original languageEnglish (US)
Pages (from-to)153-158
Number of pages6
JournalJournal of Research in Personality
Volume47
Issue number2
DOIs
StatePublished - Apr 1 2013

Keywords

  • Behavior genetics
  • DRD3
  • Dopamine
  • High-risk sport
  • Sensation seeking

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