Astroblastoma and other predominantly pediatric supratentorial papillary/epithelioid gliomas

Mohamed I.A. El Hag, Alia Hdeib, Pedro D.S.C. Ciarlini, Mark L. Cohen

Research output: Contribution to journalReview articlepeer-review

Abstract

Astroblastomas are rare primary brain tumors with no currently assigned World Health Organization grade. In their classical presentation, they are well-circumscribed supratentorial solid-cystic tumors with minimal peritumoral T2 hyperintensity. They can be difficult to distinguish from other predominantly pediatric supratentorial papillary/epithelioid gliomas, such as ependymomas, choroid plexus tumors, papillary glioneuronal tumors, papillary tumors of the pineal region, and occasionally atypical teratoid/rhabdoid tumor of the central nervous system. Distinct morphologic, immunohistochemical, and ultrastructural features aid in reaching a definitive diagnosis. In this review, we present a case of pediatric astroblastoma with a unique course and discuss the key differences and similarities between astroblastomas and other predominantly pediatric supratentorial papillary/epithelioid gliomas.

Original languageEnglish (US)
Pages (from-to)244-252
Number of pages9
JournalPathology Case Reviews
Volume18
Issue number6
DOIs
StatePublished - Dec 1 2013

Keywords

  • Astroblastoma
  • Pediatric gliomas
  • Supratentorial papillary/epithelioid glioma

Fingerprint Dive into the research topics of 'Astroblastoma and other predominantly pediatric supratentorial papillary/epithelioid gliomas'. Together they form a unique fingerprint.

Cite this