Asymmetric synthesis of α-alkylated α-amino acids via Schmidt rearrangement of α, α-bisalkylated β-keto esters

Gunda I. Georg; Xiangming Guan; Joydeep Kant

doi:10.1016/S0040-4039(00)80107-0

Asymmetric synthesis of α-alkylated α-amino acids via Schmidt rearrangement of α, α-bisalkylated β-keto esters

Gunda I. Georg, Xiangming Guan, Joydeep Kant

Medicinal Chemistry

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

α-Alkylated α-amino acids are obtained in high yield and optical purity through Schmidt rearrangement of optically active α,α-bisalkylated β-keto esters.

Original language	English (US)
Pages (from-to)	403-406
Number of pages	4
Journal	Tetrahedron Letters
Volume	29
Issue number	4
DOIs	https://doi.org/10.1016/S0040-4039(00)80107-0
State	Published - 1988

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@article{6617950d615d48198108a9f222f5e77b,

title = "Asymmetric synthesis of α-alkylated α-amino acids via Schmidt rearrangement of α, α-bisalkylated β-keto esters",

abstract = "α-Alkylated α-amino acids are obtained in high yield and optical purity through Schmidt rearrangement of optically active α,α-bisalkylated β-keto esters.",

author = "Georg, {Gunda I.} and Xiangming Guan and Joydeep Kant",

year = "1988",

doi = "10.1016/S0040-4039(00)80107-0",

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volume = "29",

pages = "403--406",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

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T1 - Asymmetric synthesis of α-alkylated α-amino acids via Schmidt rearrangement of α, α-bisalkylated β-keto esters

AU - Georg, Gunda I.

AU - Guan, Xiangming

AU - Kant, Joydeep

PY - 1988

Y1 - 1988

N2 - α-Alkylated α-amino acids are obtained in high yield and optical purity through Schmidt rearrangement of optically active α,α-bisalkylated β-keto esters.

AB - α-Alkylated α-amino acids are obtained in high yield and optical purity through Schmidt rearrangement of optically active α,α-bisalkylated β-keto esters.

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U2 - 10.1016/S0040-4039(00)80107-0

DO - 10.1016/S0040-4039(00)80107-0

M3 - Article

AN - SCOPUS:0000482680

SN - 0040-4039

VL - 29

SP - 403

EP - 406

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 4

ER -

Asymmetric synthesis of α-alkylated α-amino acids via Schmidt rearrangement of α, α-bisalkylated β-keto esters

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