TY - JOUR
T1 - Asymptomatic Primary Hyperparathyroidism in Children
T2 - Newer Methods of Preoperative Diagnosis
AU - Allen, David B.
AU - Friedman, Aaron L.
AU - Hendricks, S. Anne
PY - 1986/8
Y1 - 1986/8
N2 - An asymptomatic 11-year-old boy was found to have primary hyperparathyroid secondary to an isolated parathyroid adenoma. This rare disorder of childhood can have asymptomatic hypercalcemia as its only manifestation. Parathyroid hormone assays and studies of urinary calcium excretion, especially the calcium-creatlnine clearance ratio, distinguish parathyroid hormone excess from hypocalciuric forms of hypercalcemia, Real-time ultrasonography and dual-isotope subtraction scanning provide accurate, noninvasive, preoperative localization of abnormal parathyroid tissue. The prognosis of untreated, asymptomatic primary hyperparathyroidism in children is not known, and the indications for surgery are unclear. Diagnostic certainty is, therefore, especially important prior to surgical exploration.
AB - An asymptomatic 11-year-old boy was found to have primary hyperparathyroid secondary to an isolated parathyroid adenoma. This rare disorder of childhood can have asymptomatic hypercalcemia as its only manifestation. Parathyroid hormone assays and studies of urinary calcium excretion, especially the calcium-creatlnine clearance ratio, distinguish parathyroid hormone excess from hypocalciuric forms of hypercalcemia, Real-time ultrasonography and dual-isotope subtraction scanning provide accurate, noninvasive, preoperative localization of abnormal parathyroid tissue. The prognosis of untreated, asymptomatic primary hyperparathyroidism in children is not known, and the indications for surgery are unclear. Diagnostic certainty is, therefore, especially important prior to surgical exploration.
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U2 - 10.1001/archpedi.1986.02140220101043
DO - 10.1001/archpedi.1986.02140220101043
M3 - Article
C2 - 3524197
AN - SCOPUS:0022499966
SN - 0002-922X
VL - 140
SP - 819
EP - 821
JO - American Journal of Diseases of Children
JF - American Journal of Diseases of Children
IS - 8
ER -