Attenuated virulence of a Burkholderia cepacia type III secretion mutant in a murine model of infection

Medicine & Life Sciences

• Burkholderia cepacia 100%
• Virulence 59%
• Lung 36%
• Infections 32%
• Burkholderia Infections 28%
• Genes 27%
• Spleen 26%
• Type III Secretion Systems 23%
• Loss of Function Mutation 19%
• Proteins 18%
• Immunocompromised Host 18%
• Gram-Negative Bacteria 17%
• Cystic Fibrosis 16%
• Open Reading Frames 16%
• Inbred C57BL Mouse 16%
• Dissection 14%
• Carrier Proteins 14%
• Adenosine Triphosphate 13%
• Bacteria 11%
• Polymerase Chain Reaction 10%

Agriculture & Biology

• animal models 60%
• virulence 55%
• secretion 48%
• lungs 43%
• infection 36%
• protein secretion 32%
• mice 23%
• spleen 23%
• genes 18%
• cystic fibrosis 18%
• type III secretion system 17%
• loss-of-function mutation 17%
• pathogens 16%
• Gram-negative bacteria 13%
• pathogenesis 12%
• binding proteins 11%
• open reading frames 10%
• cells 8%
• loci 8%
• energy 8%
• bacteria 7%
• proteins 4%