Attenuation of foot-and-mouth disease virus by engineered viral polymerase fidelity

Medicine & Life Sciences

• Foot-and-Mouth Disease Virus 100%
• Viruses 48%
• RNA Replicase 24%
• Ribavirin 20%
• Growth 13%
• Kinetics 13%
• Isoleucine 11%
• Phenylalanine 10%
• Viral RNA 9%
• Tryptophan 9%
• Nucleosides 9%
• Leucine 9%
• Codon 8%
• Point Mutation 8%
• Coinfection 8%
• Fluorouracil 8%
• Molecular Biology 7%
• Swine 7%
• Vaccines 6%
• Phenotype 5%
• Kidney 4%
• Animals 4%
• Infections 4%
• In Vitro Techniques 3%

Agriculture & Biology

• Foot-and-mouth disease virus 92%
• viruses 47%
• RNA-directed RNA polymerase 22%
• fluorouracil 11%
• kinetics 11%
• point mutation 9%
• nucleosides 9%
• kidney cells 9%
• mixed infection 9%
• isoleucine 9%
• phenylalanine 8%
• codons 8%
• tryptophan 8%
• leucine 8%
• vaccines 7%
• RNA 6%
• phenotype 6%
• swine 5%
• mice 5%
• synthesis 4%
• infection 4%
• cells 2%