Au-catalyzed synthesis of 2-alkylindoles from N-arylhydroxylamines and terminal alkynes

Yanzhao Wang, Longwu Ye, Liming Zhang

Research output: Contribution to journalArticlepeer-review

71 Scopus citations

Abstract

The first gold-catalyzed addition of N-arylhydroxylamines to aliphatic terminal alkynes is developed to access O-alkenyl-N-arylhydroxylamines, which undergo facile in situ sequential 3,3-rearrangements and cyclodehydrations to afford 2-alkylindoles with regiospecificity and under exceptionally mild reaction conditions.

Original languageEnglish (US)
Pages (from-to)7815-7817
Number of pages3
JournalChemical Communications
Volume47
Issue number27
DOIs
StatePublished - 2011

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