An automated algorithm has been developed to segment stripped (non-brain tissue excluded) T1-weighted MRI brain volumes into left and right cerebral hemispheres and cerebellum + brainstem. The algorithm, which uses the Graph Cuts technique, performs a fully automated segmentation in approximately 30 s following pre-processing. It is robust and accurate and has been tested on datasets from two scanners using different field strengths and pulse sequences. We describe the Graph Cuts algorithm and compare the results of Graph Cuts segmentations against "gold standard" manual segmentations and segmentations produced by three popular software packages used by neuroimagers: BrainVisa, CLASP, and SurfRelax.
Bibliographical noteFunding Information:
We are grateful to Ms. Kristi Boesen for preparing the brainmask and to Dr. Jill Huang for creating the manual spatial compartments. This work was supported by NIH Human Brain Project Grant EB002013.
Copyright 2008 Elsevier B.V., All rights reserved.