Abstract
Auxin regulates a host of plant developmental and physiological processes, including embryogenesis, vascular differentiation, organogenesis, tropic growth, and root and shoot architecture. Genetic and biochemical studies carried out over the past decade have revealed that much of this regulation involves the SCFTIR1/AFB-mediated proteolysis of the Aux/IAA family of transcriptional regulators. With the recent finding that the TRANSPORT INHIBITOR RESPONSE1 (TIR1)/AUXIN SIGNALING F-BOX (AFB) proteins also function as auxin receptors, a potentially complete, and surprisingly simple, signaling pathway from perception to transcriptional response is now before us. However, understanding how this seemingly simple pathway controls the myriad of specific auxin responses remains a daunting challenge, and compelling evidence exists for SCFTIR1/AFB-independent auxin signaling pathways.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 448-453 |
| Number of pages | 6 |
| Journal | Current Opinion in Plant Biology |
| Volume | 9 |
| Issue number | 5 |
| DOIs | |
| State | Published - Oct 2006 |
Bibliographical note
Funding Information:We thank P Overvoorde for helpful comments on the manuscript and apologize to colleagues whose research could not be included in the available space. Research in the authors’ lab is supported by a US National Institutes of Health grant (GM067203 to WMG), and a postdoctoral fellowship from the Deutsche Forschungsgemeinschaft (to MQ).