Abstract
A/W bioactive glass (BG) particles (600-1000 microns) were soaked in 0.1 M 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) solutions (0.01 g BG per 1 mL solution) at three pH ranges (acidic: 4.45-6.31, neutral: 7.45-7.64 and basic: 10.31-10.42). Crystalline calcium phosphates developed on BG surfaces after soaking in either acidic or neutral solutions. Electron diffraction (ED) results showed that whitlockite and octa-calcium phosphate (OCP) were the newly developed materials on BG in the acidic HEPES solution after soaking for 7 d and 14 d, respectively. Whitlockite also developed on the BG particles in the neutral solution of 0.5Na-HEPES after soaking for 14 d. No crystalline materials developed on BG surfaces after soaking in the basic Na-HEPES solution up to 14 d. The results of this study demonstrated that.the pH of a soaking solution strongly affect both the ions release of the A/W BG particles, and the development of crystalline calcium phosphates on BG particles.
Original language | English (US) |
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Pages (from-to) | 501-504 |
Number of pages | 4 |
Journal | Key Engineering Materials |
Volume | 284-286 |
DOIs | |
State | Published - Jan 1 2005 |
Keywords
- Bioactive glass
- Calcium phosphates
- HEPES
- Mineralization
- pH