B-cell lymphopoiesis in mouse and man

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Functional immunoglobulin gene rearrangement is a sine qua non for successful B cell development in mammalian bone marrow, but other factors are also important. Studies reported during the past year have contributed new insight into the surface receptor complexes and signaling outcomes that influence the fate of B cell precursors. Identification and characterization of secreted and membrane-associated stromal cell products, and their actions on B-cell precursors, was a parallel area of ongoing investigation.

Original languageEnglish (US)
Pages (from-to)188-195
Number of pages8
JournalCurrent Opinion in Immunology
Issue number2
StatePublished - Apr 1998

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