Baseline characteristics of African Americans in the Systolic Blood Pressure Intervention Trial

Carolyn H. Still; Timothy E. Craven; Barry I. Freedman; Peter N. Van Buren; Kaycee M. Sink; Anthony A. Killeen; Jeffrey T. Bates; Alberta Bee; Gabriel Contreras; Suzanne Oparil; Carolyn M. Pedley; Barry M. Wall; Suzanne White; Delia M. Woods; Carlos J. Rodriguez; Jackson T. Wright

doi:10.1016/j.jash.2015.06.012

Baseline characteristics of African Americans in the Systolic Blood Pressure Intervention Trial

Carolyn H. Still, Timothy E. Craven, Barry I. Freedman, Peter N. Van Buren, Kaycee M. Sink, Anthony A. Killeen, Jeffrey T. Bates, Alberta Bee, Gabriel Contreras, Suzanne Oparil, Carolyn M. Pedley, Barry M. Wall, Suzanne White, Delia M. Woods, Carlos J. Rodriguez, Jackson T. Wright

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

The Systolic Blood Pressure Intervention Trial (SPRINT) will compare treatment to a systolic blood pressure goal of <120 mm Hg to treatment to the currently recommended goal of <140 mm Hg for effects on incident cardiovascular, renal, and neurologic outcomes including cognitive decline. The objectives of this analysis are to compare baseline characteristics of African American (AA) and non-AA SPRINT participants and explore factors associated with uncontrolled blood pressure (BP) by race. SPRINT enrolled 9361 hypertensive participants aged older than 50 years. This cross-sectional analysis examines sociodemographics, baseline characteristics, and study measures among AAs compared with non-AAs. AAs made up 31% of participants. AAs (compared with non-AAs) were younger and less frequently male, had less education, and were more likely uninsured or covered by Medicaid. In addition, AAs scored lower on the cognitive screening test when compared with non-AAs. Multivariate logistic regression analysis found BP control rates to <140/90 mm Hg were higher for AAs who were male, had higher number of chronic diseases, were on diuretic treatment, and had better medication adherence. SPRINT is well poised to examine the effects of systolic blood pressure targets on clinical outcomes as well as predictors influencing BP control in AAs.

Original language	English (US)
Pages (from-to)	670-679
Number of pages	10
Journal	Journal of the American Society of Hypertension
Volume	9
Issue number	9
DOIs	https://doi.org/10.1016/j.jash.2015.06.012
State	Published - Sep 1 2015

Bibliographical note

Publisher Copyright:
© 2015 American Society of Hypertension.

Keywords

Cardiovascular disease
SPRINT
blacks
clinical trials
hypertension

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Still, C. H., Craven, T. E., Freedman, B. I., Van Buren, P. N., Sink, K. M., Killeen, A. A., Bates, J. T., Bee, A., Contreras, G., Oparil, S., Pedley, C. M., Wall, B. M., White, S., Woods, D. M., Rodriguez, C. J., & Wright, J. T. (2015). Baseline characteristics of African Americans in the Systolic Blood Pressure Intervention Trial. Journal of the American Society of Hypertension, 9(9), 670-679. https://doi.org/10.1016/j.jash.2015.06.012

Still, CH, Craven, TE, Freedman, BI, Van Buren, PN, Sink, KM, Killeen, AA, Bates, JT, Bee, A, Contreras, G, Oparil, S, Pedley, CM, Wall, BM, White, S, Woods, DM, Rodriguez, CJ & Wright, JT 2015, 'Baseline characteristics of African Americans in the Systolic Blood Pressure Intervention Trial', Journal of the American Society of Hypertension, vol. 9, no. 9, pp. 670-679. https://doi.org/10.1016/j.jash.2015.06.012

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Baseline characteristics of African Americans in the Systolic Blood Pressure Intervention Trial

Abstract

Bibliographical note

Keywords

UN SDGs

Access

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