Bisphosphonate therapy for the treatment of skeletal complications in patients with prostate cancer

Andrea L. Harzstark; Charles J. Ryan; Eric J. Small

doi:10.2217/1745509X.2.6.943

Bisphosphonate therapy for the treatment of skeletal complications in patients with prostate cancer

Andrea L. Harzstark, Charles J. Ryan, Eric J. Small

Research output: Contribution to journal › Review article › peer-review

Abstract

Osseous metastases and osteoporotic fractures are a serious problem in patients with prostate cancer. As androgen-deprivation therapy is being used earlier in the course of the disease, the risk of osteoporosis and insufficiency fractures is increasing. In this review, the contribution of androgen-deprivation therapy to osteoporosis and bone metastases will be discussed. The role of bisphosphonates in treating osteoporosis and bone metastases will also be reviewed. The review will conclude with a discussion of the toxicities associated with bisphosphonate use.

Original language	English (US)
Pages (from-to)	943-954
Number of pages	12
Journal	Aging Health
Volume	2
Issue number	6
DOIs	https://doi.org/10.2217/1745509X.2.6.943
State	Published - Dec 1 2006
Externally published	Yes

Keywords

Bisphosphonates
Bone metastasis
Prostate cancer
Skeletal complications of malignancy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access

10.2217/1745509X.2.6.943

OpenUrl availability

Full text

Cite this

@article{0092824ce3c4427bb2d690844eb84361,

title = "Bisphosphonate therapy for the treatment of skeletal complications in patients with prostate cancer",

abstract = "Osseous metastases and osteoporotic fractures are a serious problem in patients with prostate cancer. As androgen-deprivation therapy is being used earlier in the course of the disease, the risk of osteoporosis and insufficiency fractures is increasing. In this review, the contribution of androgen-deprivation therapy to osteoporosis and bone metastases will be discussed. The role of bisphosphonates in treating osteoporosis and bone metastases will also be reviewed. The review will conclude with a discussion of the toxicities associated with bisphosphonate use.",

keywords = "Bisphosphonates, Bone metastasis, Prostate cancer, Skeletal complications of malignancy",

author = "Harzstark, {Andrea L.} and Ryan, {Charles J.} and Small, {Eric J.}",

year = "2006",

month = dec,

day = "1",

doi = "10.2217/1745509X.2.6.943",

language = "English (US)",

volume = "2",

pages = "943--954",

journal = "Aging Health",

issn = "1745-509X",

publisher = "Future Medicine Ltd.",

number = "6",

}

TY - JOUR

T1 - Bisphosphonate therapy for the treatment of skeletal complications in patients with prostate cancer

AU - Harzstark, Andrea L.

AU - Ryan, Charles J.

AU - Small, Eric J.

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Osseous metastases and osteoporotic fractures are a serious problem in patients with prostate cancer. As androgen-deprivation therapy is being used earlier in the course of the disease, the risk of osteoporosis and insufficiency fractures is increasing. In this review, the contribution of androgen-deprivation therapy to osteoporosis and bone metastases will be discussed. The role of bisphosphonates in treating osteoporosis and bone metastases will also be reviewed. The review will conclude with a discussion of the toxicities associated with bisphosphonate use.

AB - Osseous metastases and osteoporotic fractures are a serious problem in patients with prostate cancer. As androgen-deprivation therapy is being used earlier in the course of the disease, the risk of osteoporosis and insufficiency fractures is increasing. In this review, the contribution of androgen-deprivation therapy to osteoporosis and bone metastases will be discussed. The role of bisphosphonates in treating osteoporosis and bone metastases will also be reviewed. The review will conclude with a discussion of the toxicities associated with bisphosphonate use.

KW - Bisphosphonates

KW - Bone metastasis

KW - Prostate cancer

KW - Skeletal complications of malignancy

UR - http://www.scopus.com/inward/record.url?scp=33845874365&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33845874365&partnerID=8YFLogxK

U2 - 10.2217/1745509X.2.6.943

DO - 10.2217/1745509X.2.6.943

M3 - Review article

AN - SCOPUS:33845874365

SN - 1745-509X

VL - 2

SP - 943

EP - 954

JO - Aging Health

JF - Aging Health

IS - 6

ER -

Bisphosphonate therapy for the treatment of skeletal complications in patients with prostate cancer

Abstract

Keywords

UN SDGs

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this