Block Polymer Micelles Enable CRISPR/Cas9 Ribonucleoprotein Delivery: Physicochemical Properties Affect Packaging Mechanisms and Gene Editing Efficiency

Zhe Tan; Yaming Jiang; Mitra S. Ganewatta; Ramya Kumar; Allison Keith; Kirk Twaroski; Thomas Pengo; Jakub Tolar; Timothy P. Lodge; Theresa M. Reineke

doi:10.1021/acs.macromol.9b01645

Block Polymer Micelles Enable CRISPR/Cas9 Ribonucleoprotein Delivery: Physicochemical Properties Affect Packaging Mechanisms and Gene Editing Efficiency

Zhe Tan, Yaming Jiang, Mitra S. Ganewatta, Ramya Kumar, Allison Keith, Kirk Twaroski, Thomas Pengo, Jakub Tolar, Timothy P. Lodge, Theresa M. Reineke

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Original language	English (US)
Journal	Macromolecules
DOIs	https://doi.org/10.1021/acs.macromol.9b01645
State	Published - Oct 21 2019

How much support was provided by MRSEC?

Partial

Reporting period for MRSEC

Period 6

Access

10.1021/acs.macromol.9b01645

https://pubs.acs.org/doi/10.1021/acs.macromol.9b01645

OpenUrl availability

Full text

1 Finished
1 Active

MRSEC IRG-3: Hierarchical Multifunctional Macromolecular Materials
Reineke, T. M., Bates, F. S., Dorfman, K., Dutcher, C. S., Hillmyer, M. A., Lodge, T., Morse, D. C., Siepmann, I., Barreda, L. & Ganewatta, M. S.
1/1/98 → …
Project: Research project
University of Minnesota MRSEC (DMR-1420013)
Lodge, T.
11/1/14 → 10/31/20
Project: Research project

University Imaging Centers
Mark A Sanders (Program Director) & Guillermo Marques (Scientific Director)
University Imaging Centers
Equipment/facility: Facility
Zeiss TIRF Scope
University Imaging Centers
Equipment/facility: Equipment

Cite this

@article{391473eb1b434ffd902d9666b98e2ceb,

title = "Block Polymer Micelles Enable CRISPR/Cas9 Ribonucleoprotein Delivery: Physicochemical Properties Affect Packaging Mechanisms and Gene Editing Efficiency",

author = "Zhe Tan and Yaming Jiang and Ganewatta, {Mitra S.} and Ramya Kumar and Allison Keith and Kirk Twaroski and Thomas Pengo and Jakub Tolar and Lodge, {Timothy P.} and Reineke, {Theresa M.}",

year = "2019",

month = oct,

day = "21",

doi = "10.1021/acs.macromol.9b01645",

language = "English (US)",

journal = "Macromolecules",

issn = "0024-9297",

publisher = "American Chemical Society",

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T1 - Block Polymer Micelles Enable CRISPR/Cas9 Ribonucleoprotein Delivery: Physicochemical Properties Affect Packaging Mechanisms and Gene Editing Efficiency

AU - Tan, Zhe

AU - Jiang, Yaming

AU - Ganewatta, Mitra S.

AU - Kumar, Ramya

AU - Keith, Allison

AU - Twaroski, Kirk

AU - Pengo, Thomas

AU - Tolar, Jakub

AU - Lodge, Timothy P.

AU - Reineke, Theresa M.

PY - 2019/10/21

Y1 - 2019/10/21

U2 - 10.1021/acs.macromol.9b01645

DO - 10.1021/acs.macromol.9b01645

M3 - Article

SN - 0024-9297

JO - Macromolecules

JF - Macromolecules

ER -

Block Polymer Micelles Enable CRISPR/Cas9 Ribonucleoprotein Delivery: Physicochemical Properties Affect Packaging Mechanisms and Gene Editing Efficiency

How much support was provided by MRSEC?

Reporting period for MRSEC

Access

OpenUrl availability

Projects

MRSEC IRG-3: Hierarchical Multifunctional Macromolecular Materials

University of Minnesota MRSEC (DMR-1420013)

Equipment

University Imaging Centers

Zeiss TIRF Scope

Cite this