Bovine tuberculosis in domestic pigs: Genotyping and distribution of isolates in Argentina

S. Barandiaran, M. Martínez Vivot, A. M. Pérez, A. A. Cataldi, M. J. Zumárraga

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Bovine tuberculosis is caused by Mycobacterium bovis and affects primarily cattle, among many other mammal species. In this study, 250 isolates of M. bovis collected from pigs slaughtered in Argentina were typed by spoligotyping. Over half of the isolates (66%) grouped into two spoligotypes. Moreover, SB0140 was the most frequent spoligotype detected in the three performed samplings. In addition, 195 isolates were typed through variable number of tandem repeats (VNTR) by selecting 7 loci (MIRU 16-26-31 and ETR A-B-C-D). The relationship among the patterns was performed using a goeBURST algorithm and the main clonal complexes grouped 110 isolates (56%). Although pigs shared genotypes with cattle (n=21), some patterns were detected only in pigs (n=14). These findings suggest the pig as a source of M. bovis infection to cattle.

Original languageEnglish (US)
Pages (from-to)44-50
Number of pages7
JournalResearch in veterinary science
Volume103
DOIs
StatePublished - Dec 1 2015

Bibliographical note

Funding Information:
We thank Dr Julia Sabio y García for their critical reading of this manuscript. A.A.C. and M.J.Z. are career members of CONICET, Argentina. S.B. holds a fellowship from CONICET, Argentina. This work was supported by the National Institute of Agricultural Technology ( AESA 202·831 ) and UBA ( UBACyT 20020100100203 ) grants.

Publisher Copyright:
© 2015 Elsevier Ltd.

Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.

Keywords

  • Mycobacterium bovis
  • Pigs
  • Spoligotyping
  • VNTR

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