Volatile sulfur compounds are known to be major contributors to oral malodor, and their detection by gas chromatography (GC) is a commonly used method for evaluating breath odor in clinical trials. A custom-designed breath-sampling GC system was developed for this purpose. A clinical study was performed to compare the performance of this instrumental method to organoleptic evaluation by trained odor judges. A statistically significant correlation was found between the measured levels of volatile sulfurs and the ratings of the odor judges. Both methods performed similarly in evaluating the breath-freshening effects of two test products. These results demonstrate the strength of the GC method for evaluating breath odor and predicting the breath-freshening effects of oral-care products.
|Original language||English (US)|
|Pages (from-to)||25-28; quiz 43|
|Journal||Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)|
|Issue number||9 Suppl|
|State||Published - Sep 2003|