TY - JOUR
T1 - Brugada-like electrocardiography pattern induced by severe hyponatraemia
AU - Tamene, Ashenafi M
AU - Sattiraju, Srinivasan
AU - Wang, Kyuhyun
AU - Benditt, David G
PY - 2010/6
Y1 - 2010/6
N2 - The characteristic electrocardiographic (ECG) findings of Brugada syndrome,1 specifically the down sloping coved elevation of the ST-segment ending in an inverted T-wave in the right precordial leads, have been linked to reduced inward sodium current due to dysfunctional sodium channels.2 Additionally, however, many sodium channel blocking agents are known to either unmask or induce this ECG pattern.3 Severe hyponatraemia may be expected to have the same effect by reducing inward sodium current. Here, we report a case in which the presenting ECG exhibited a 'Brugada-like' pattern during severe isolated hyponatraemia, with subsequent normalization as hyponatraemia improved.
AB - The characteristic electrocardiographic (ECG) findings of Brugada syndrome,1 specifically the down sloping coved elevation of the ST-segment ending in an inverted T-wave in the right precordial leads, have been linked to reduced inward sodium current due to dysfunctional sodium channels.2 Additionally, however, many sodium channel blocking agents are known to either unmask or induce this ECG pattern.3 Severe hyponatraemia may be expected to have the same effect by reducing inward sodium current. Here, we report a case in which the presenting ECG exhibited a 'Brugada-like' pattern during severe isolated hyponatraemia, with subsequent normalization as hyponatraemia improved.
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U2 - 10.1093/europace/euq034
DO - 10.1093/europace/euq034
M3 - Article
C2 - 20185483
AN - SCOPUS:77953003785
SN - 1099-5129
VL - 12
SP - 905
EP - 907
JO - Europace
JF - Europace
IS - 6
ER -