TY - GEN
T1 - Carbon nanotubes swine influenza (H1N1) virus sensors
AU - Lee, Dongjin
AU - Chander, Yogesh
AU - Goyal, Sagar M.
AU - Cui, Tianhong
PY - 2010
Y1 - 2010
N2 - We present a label-free detection of swine influenza virus (SIV) H1N1 by means of the excellent electrical properties of single-walled carbon nanotubes (SWCNTs). The electrical resistance of SWCNT resistor tends to increase upon the surface adsorption of macromolecules such as poly-L-lysine, anti-SIV antibodies, and SIVs in the process of immunoassay. The SWCNT network resistor was successfully able to detect as low as 180 TCID50/ml of SIV using the resistance shifts upon immunobinding of SIVs. The sensor specificity was demonstrated against transmissible gastroenteritis virus (TGEV) and feline calicivirus (FCV). This facile CNT-based immnoassay has potential applications as a rapid point-of-care detection or a sensing platform for lab-on-a-chip systems.
AB - We present a label-free detection of swine influenza virus (SIV) H1N1 by means of the excellent electrical properties of single-walled carbon nanotubes (SWCNTs). The electrical resistance of SWCNT resistor tends to increase upon the surface adsorption of macromolecules such as poly-L-lysine, anti-SIV antibodies, and SIVs in the process of immunoassay. The SWCNT network resistor was successfully able to detect as low as 180 TCID50/ml of SIV using the resistance shifts upon immunobinding of SIVs. The sensor specificity was demonstrated against transmissible gastroenteritis virus (TGEV) and feline calicivirus (FCV). This facile CNT-based immnoassay has potential applications as a rapid point-of-care detection or a sensing platform for lab-on-a-chip systems.
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U2 - 10.1115/IMECE2010-40735
DO - 10.1115/IMECE2010-40735
M3 - Conference contribution
AN - SCOPUS:84881466949
SN - 9780791844267
T3 - ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
SP - 49
EP - 52
BT - ASME 2010 International Mechanical Engineering Congress and Exposition, IMECE 2010
T2 - ASME 2010 International Mechanical Engineering Congress and Exposition, IMECE 2010
Y2 - 12 November 2010 through 18 November 2010
ER -
