Cardio-oncology Related to Heart Failure: Common Risk Factors Between Cancer and Cardiovascular Disease

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18 Scopus citations

Abstract

There is a growing body of evidence that suggests cancer and cardiovascular disease have a shared biological mechanism. Although there are several shared risk factors for both diseases, including advancing age, gender, obesity, diabetes, physical activity, tobacco use, and diet, inflammation and biomarkers, such as insulinlike growth factor 1, leptin, estrogen, and adiponectin, may also play a role in the biology of these diseases. This article provides an overview of the shared biological mechanism between cancer and cardiovascular disease.

Original languageEnglish (US)
Pages (from-to)367-380
Number of pages14
JournalHeart Failure Clinics
Volume13
Issue number2
DOIs
StatePublished - Apr 1 2017

Bibliographical note

Funding Information:
Funding: A. Prizment was supported by the National Center for Advancing Translational Sciences of the National Institute of Health (NIH)Award Number UL1 TR000114. A. Blaes was supported by the Building Interdisciplinary Research Careers in Women's Health (NIH #K12-HD055887).

Publisher Copyright:
© 2017 Elsevier Inc.

Keywords

  • Cancer
  • Cardiooncology
  • Heart disease
  • Risk
  • Risk factors

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