There is a growing body of evidence that suggests cancer and cardiovascular disease have a shared biological mechanism. Although there are several shared risk factors for both diseases, including advancing age, gender, obesity, diabetes, physical activity, tobacco use, and diet, inflammation and biomarkers, such as insulinlike growth factor 1, leptin, estrogen, and adiponectin, may also play a role in the biology of these diseases. This article provides an overview of the shared biological mechanism between cancer and cardiovascular disease.
Bibliographical noteFunding Information:
Funding: A. Prizment was supported by the National Center for Advancing Translational Sciences of the National Institute of Health (NIH)Award Number UL1 TR000114. A. Blaes was supported by the Building Interdisciplinary Research Careers in Women's Health (NIH #K12-HD055887).
© 2017 Elsevier Inc.
- Heart disease
- Risk factors