Cardiorenal syndrome: A cardiologist's perspective of pathophysiology

Inder Anand

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


The cardiorenal syndrome has recently been defined as "disorders of the heart and kidney whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other." The syndrome is extremely common and independently associated with poor clinical outcomes. However, no pharmacological therapy has been shown to improve its outcomes. Unfortunately, the mechanisms that initiate the development of renal dysfunction in heart failure are still debated. This review tries to clarify some of the misunderstanding regarding the principle hemodynamic factors that drive the kidneys to retain salt and water.

Original languageEnglish (US)
Pages (from-to)1800-1807
Number of pages8
JournalClinical Journal of the American Society of Nephrology
Issue number10
StatePublished - Oct 7 2013

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