Die karotisstenose im fokus klinischer studien chirurgie, angioplastie oder medikamentöse therapie?

Translated title of the contribution: Carotid occlusive disease focused by clinical studies - Surgery, angioplasty or drug treatment?

Marius Hornung, Stefan C. Bertog, Jennifer Franke, Nina Wunderlich, Horst Sievert

Research output: Contribution to journalReview articlepeer-review

Abstract

The benefit of carotid surgery compared to medical treatment in patients who suffer from symptomatic carotid stenosis as well as from asymptomatic ones has been shown in the early 1990s by several randomized trials (NASCET, ECST, ACAS, ACST). Carotid stenting is one of the most dynamic and innovative fields in the area of vascular interventions and is now performed routinely in many centers worldwide. Nevertheless, despite similar trial results comparing both interventions (CAVATAS, SPACE), there is still no general agreement whether stenting should be accepted as an alternative method to surgery or not. But due to the interventionalists' gaining expertise and experience as well as the design of new stents, filters and embolic protection devices with already completed trials (CREST) as well as ongoing trials (TACIT, ICSS, ACT 1) may to prove equivalence or even superiority of carotid artery stenting compared to surgery.

Translated title of the contributionCarotid occlusive disease focused by clinical studies - Surgery, angioplasty or drug treatment?
Original languageGerman
Pages (from-to)284-290
Number of pages7
JournalKlinikarzt
Volume38
Issue number6
DOIs
StatePublished - Aug 10 2009

Keywords

  • Angioplasty
  • Carotid artery disease
  • Carotid stent
  • Endarterectomy
  • Prevention
  • Stroke

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