Case Studies Illustrating Focal Alzheimer's, Fluent Aphasia, Late-Onset Memory Loss, and Rapid Dementia

Gamze Balci Camsari; Melissa E. Murray; Neill R. Graff-Radford

doi:10.1016/j.ncl.2016.04.008

Case Studies Illustrating Focal Alzheimer's, Fluent Aphasia, Late-Onset Memory Loss, and Rapid Dementia

Gamze Balci Camsari, Melissa E. Murray, Neill R. Graff-Radford

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Many dementia subtypes have more shared signs and symptoms than defining ones. We review 8 cases with 4 overlapping syndromes and demonstrate how to distinguish the cases. These include focal cortical presentations of Alzheimer's disease (AD; posterior cortical atrophy and corticobasal syndrome [CBS]), fluent aphasia (semantic dementia and logopenic aphasia), late-onset slowly progressive dementia (hippocampal sclerosis and limbic predominant AD) and rapidly progressive dementia (Creutzfeldt–Jakob disease and limbic encephalitis). Recognizing the different syndromes can help the clinician to improve their diagnostic skills, leading to improved patient outcomes by early and accurate diagnosis, prompt treatment, and appropriate counseling and guidance.

Original language	English (US)
Pages (from-to)	699-716
Number of pages	18
Journal	Neurologic Clinics
Volume	34
Issue number	3
DOIs	https://doi.org/10.1016/j.ncl.2016.04.008
State	Published - Aug 1 2016
Externally published	Yes

Bibliographical note

Funding Information:
Disclosures: Dr. Murray is partly supported by Donors Cure Foundation New Vision Award and Gerstner Family Career Development Award. The study is supported in part by Mayo Clinic Alzheimer's Disease Research Center (ADRC) grant P50AG 16574-14 (PI: Ronald Petersen, MD, PhD). The authors have nothing to disclose.

Publisher Copyright:
© 2016 Elsevier Inc.

Keywords

Atypical Alzheimer's
Fluent aphasia
Late-onset dementia
Rapid dementia

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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abstract = "Many dementia subtypes have more shared signs and symptoms than defining ones. We review 8 cases with 4 overlapping syndromes and demonstrate how to distinguish the cases. These include focal cortical presentations of Alzheimer's disease (AD; posterior cortical atrophy and corticobasal syndrome [CBS]), fluent aphasia (semantic dementia and logopenic aphasia), late-onset slowly progressive dementia (hippocampal sclerosis and limbic predominant AD) and rapidly progressive dementia (Creutzfeldt–Jakob disease and limbic encephalitis). Recognizing the different syndromes can help the clinician to improve their diagnostic skills, leading to improved patient outcomes by early and accurate diagnosis, prompt treatment, and appropriate counseling and guidance.",

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Case Studies Illustrating Focal Alzheimer's, Fluent Aphasia, Late-Onset Memory Loss, and Rapid Dementia

Abstract

Bibliographical note

Keywords

UN SDGs

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