Case studies in the management of refractory bleeding in patients with haemophilia A and inhibitors

L. A. Valentino, G. Allen, J. C. Gill, A. Hurlet, B. A. Konkle, C. A. Leissinger, L. Luchtman-Jones, J. Powell, M. Reding, K. Stine

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

In haemophilia patients with well-established high-titer inhibitors, even seemingly minor acute bleeding episodes or surgical procedures may become refractory to treatment and transform into limb- or life-threatening situations. In the absence of evidence-based treatment guidelines, this article presents 10 cases of difficult to control acute and surgical bleeding and offers consensus opinions regarding their management from a panel of experienced haemophilia treaters.

Original languageEnglish (US)
Pages (from-to)e151-e166
JournalHaemophilia
Volume19
Issue number3
DOIs
StatePublished - May 1 2013

Keywords

  • Adjuvant therapy
  • Bypassing therapy
  • Haemophilia A
  • Inhibitors
  • Refractory bleeding

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