Cavitation in bacteremic pneumococcal pneumonia. Causal role of mixed infection with anaerobic bacteria

James W Leatherman, Conrad Iber, Scott F Davies

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Cavitation developed in 4 of 24 patients with bacteremic pneumococcal pneumonia seen in 1 yr. Two of them had roentgenographic evidence of massive pulmonary gangrene. A total of 3 patients developed putrid sputum at the time of cavitation, proving that anaerobes were present. Culture confirmation of anaerobic etiology (Bacteroides fragilis) was obtained in 1 patient who had a thoracotomy for pulmonary gangrene, Putrid sputum was observed only in cavitary cases. Other clinical and epidemiological features (bilateral infiltrates, alcoholism), which were more frequent in cavitary than in noncavitary cases, are often associated with anaerobic infection. These findings support the hypothesis that concomitant anaerobic infection may be responsible for cavitation in bacteremic pneumococcal pneumonia.

Original languageEnglish (US)
Pages (from-to)317-321
Number of pages5
JournalAmerican Review of Respiratory Disease
Volume129
Issue number2
StatePublished - Jan 1 1984

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