Cell growth inhibition by 3-deoxysappanchalcone is mediated by directly targeting the TOPK signaling pathway in colon cancer

Medicine & Life Sciences

• 3-deoxysappanchalcone 100%
• Colonic Neoplasms 39%
• Growth 22%
• Phosphotransferases 11%
• Caesalpinia 8%
• East Asian Traditional Medicine 7%
• Caspase 7 7%
• Ribosomal Protein S6 Kinases 6%
• G2 Phase Cell Cycle Checkpoints 6%
• Lymphokine-Activated Killer Cells 6%
• Cyclin B1 6%
• Cell Proliferation 6%
• Apoptosis 5%
• Mitogen-Activated Protein Kinase 3 5%
• Propidium 5%
• Mitogen-Activated Protein Kinase 1 5%
• Annexin A5 5%
• Mitogen-Activated Protein Kinases 4%
• Protein Kinases 4%
• Caspase 3 4%
• Colorectal Neoplasms 3%
• Cause of Death 3%
• Cell Cycle 3%
• Cell Survival 3%
• Proteins 3%
• Western Blotting 3%
• Staining and Labeling 3%
• Neoplasms 3%
• Inflammation 2%
• Drug Therapy 2%
• Recurrence 2%
• In Vitro Techniques 2%
• Therapeutics 1%

Chemical Compounds

• Cell Growth Inhibition 63%
• Protein 18%
• Propidium 17%
• Western Blotting 13%
• Resistance 6%