Cell transplantation for ischemic heart disease

Mohammad N. Jameel; Joseph Lee; Daniel J. Garry; Jianyi Zhang

doi:10.1007/978-1-60327-372-5_37

Cell transplantation for ischemic heart disease

Mohammad N. Jameel, Joseph Lee, Daniel J. Garry, Jianyi Zhang

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Cardiomyocyte regeneration may occur during physiological and pathological states in the adult heart; these data highlight the possibility that myocardial regeneration may occur via cardiomyocyte proliferation and/or differentiation of putative cardiac stem cells. To date, various cell types have been used for cardiac repair, including skeletal myoblasts, bone marrow-derived cells, mesenchymal stem cells, endothelial progenitor cells, umbilical cord blood stem cells, cardiac stem cells, and embryonic stem cells. This chapter will review each of these different stem cell populations in regard to the potential treatment of heart disease. It begins by examining the in vitro and in vivo animal studies, and then briefly discusses the cell therapy clinical trials that are currently underway for treating ischemic heart disease.

Original language	English (US)
Title of host publication	Handbook of Cardiac Anatomy, Physiology, and Devices
Subtitle of host publication	Second Edition
Publisher	Humana Press
Pages	613-629
Number of pages	17
ISBN (Print)	9781588294432
DOIs	https://doi.org/10.1007/978-1-60327-372-5_37
State	Published - Dec 1 2005

Keywords

Adult stem cells
Bone marrow-derived stem cells
Cardiac stem cells
Embryonic stem cells
Endothelial progenitor cells
Mesenchymal stem cells
Skeletal myoblasts
Umbilical cord blood stem cells

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Cell transplantation for ischemic heart disease",

abstract = "Cardiomyocyte regeneration may occur during physiological and pathological states in the adult heart; these data highlight the possibility that myocardial regeneration may occur via cardiomyocyte proliferation and/or differentiation of putative cardiac stem cells. To date, various cell types have been used for cardiac repair, including skeletal myoblasts, bone marrow-derived cells, mesenchymal stem cells, endothelial progenitor cells, umbilical cord blood stem cells, cardiac stem cells, and embryonic stem cells. This chapter will review each of these different stem cell populations in regard to the potential treatment of heart disease. It begins by examining the in vitro and in vivo animal studies, and then briefly discusses the cell therapy clinical trials that are currently underway for treating ischemic heart disease.",

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AU - Lee, Joseph

AU - Garry, Daniel J.

AU - Zhang, Jianyi

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N2 - Cardiomyocyte regeneration may occur during physiological and pathological states in the adult heart; these data highlight the possibility that myocardial regeneration may occur via cardiomyocyte proliferation and/or differentiation of putative cardiac stem cells. To date, various cell types have been used for cardiac repair, including skeletal myoblasts, bone marrow-derived cells, mesenchymal stem cells, endothelial progenitor cells, umbilical cord blood stem cells, cardiac stem cells, and embryonic stem cells. This chapter will review each of these different stem cell populations in regard to the potential treatment of heart disease. It begins by examining the in vitro and in vivo animal studies, and then briefly discusses the cell therapy clinical trials that are currently underway for treating ischemic heart disease.

AB - Cardiomyocyte regeneration may occur during physiological and pathological states in the adult heart; these data highlight the possibility that myocardial regeneration may occur via cardiomyocyte proliferation and/or differentiation of putative cardiac stem cells. To date, various cell types have been used for cardiac repair, including skeletal myoblasts, bone marrow-derived cells, mesenchymal stem cells, endothelial progenitor cells, umbilical cord blood stem cells, cardiac stem cells, and embryonic stem cells. This chapter will review each of these different stem cell populations in regard to the potential treatment of heart disease. It begins by examining the in vitro and in vivo animal studies, and then briefly discusses the cell therapy clinical trials that are currently underway for treating ischemic heart disease.

KW - Adult stem cells

KW - Bone marrow-derived stem cells

KW - Cardiac stem cells

KW - Embryonic stem cells

KW - Endothelial progenitor cells

KW - Mesenchymal stem cells

KW - Skeletal myoblasts

KW - Umbilical cord blood stem cells

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BT - Handbook of Cardiac Anatomy, Physiology, and Devices

PB - Humana Press

ER -

Cell transplantation for ischemic heart disease

Abstract

Keywords

UN SDGs

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