Cellular aspects of Burkholderia cepacia infection

Christian D Mohr, Mladen Tomich, Christine A. Herfst

Research output: Contribution to journalReview articlepeer-review

42 Scopus citations


The Gram-negative bacterium Burkholderia cepacia has recently emerged as an important opportunistic pathogen in humans. This review focuses on the cellular aspects of B. cepacia infection and the dynamics of the B. cepacia-host cell interaction, including recent advances in our understanding of the ability of B. cepacia to adhere to, enter, and survive intracellularly within human cells.

Original languageEnglish (US)
Pages (from-to)425-435
Number of pages11
JournalMicrobes and Infection
Issue number5
StatePublished - Apr 2001

Bibliographical note

Funding Information:
We thank Jane Burns for kindly providing the electron micrographs shown in figure 1 . This work was supported by grants from the Minnesota Medical Foundation (MRF13700) and the CF Foundation.

Copyright 2017 Elsevier B.V., All rights reserved.


  • Burkholderia cepacia
  • Infection
  • Pathogenicity


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