The Gram-negative bacterium Burkholderia cepacia has recently emerged as an important opportunistic pathogen in humans. This review focuses on the cellular aspects of B. cepacia infection and the dynamics of the B. cepacia-host cell interaction, including recent advances in our understanding of the ability of B. cepacia to adhere to, enter, and survive intracellularly within human cells.
Bibliographical noteFunding Information:
We thank Jane Burns for kindly providing the electron micrographs shown in figure 1 . This work was supported by grants from the Minnesota Medical Foundation (MRF13700) and the CF Foundation.
Copyright 2017 Elsevier B.V., All rights reserved.
- Burkholderia cepacia