TY - JOUR
T1 - Changing drug choice through conditioned reinforcement
T2 - Comment on Alessi, Roll, Reilly, and Johanson (2002)
AU - Carroll, Marilyn E.
PY - 2002/1/1
Y1 - 2002/1/1
N2 - The study by S. M. Alessi, J. M. Roll, M. P. Reilly, and C.-E. Johanson (2002) showed that in human volunteers a choice of placebo over diazepam could be reversed by pairing the drug with a higher monetary reward and the placebo with a lower monetary reward for performance on a computer-based task. The results provide a clear laboratory model of how initially neutral or aversive effects of a drug can be altered by association with positive reinforcement to establish the drug as a conditioned reinforcer and to generate drug-seeking behavior. Parallels from the animal and human literatures are discussed, as are potential future studies and applications of this approach for preventing and reducing drug abuse in humans.
AB - The study by S. M. Alessi, J. M. Roll, M. P. Reilly, and C.-E. Johanson (2002) showed that in human volunteers a choice of placebo over diazepam could be reversed by pairing the drug with a higher monetary reward and the placebo with a lower monetary reward for performance on a computer-based task. The results provide a clear laboratory model of how initially neutral or aversive effects of a drug can be altered by association with positive reinforcement to establish the drug as a conditioned reinforcer and to generate drug-seeking behavior. Parallels from the animal and human literatures are discussed, as are potential future studies and applications of this approach for preventing and reducing drug abuse in humans.
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U2 - 10.1037/1064-1297.10.2.87
DO - 10.1037/1064-1297.10.2.87
M3 - Short survey
C2 - 12022803
AN - SCOPUS:0036251208
SN - 1064-1297
VL - 10
SP - 87
EP - 89
JO - Experimental and Clinical Psychopharmacology
JF - Experimental and Clinical Psychopharmacology
IS - 2
ER -