Characterisation of ceftiofur resistance in swine bacterial pathogens

Yogesh Chander, Simone Oliveira, Sagar M. Goyal

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

A PCR based method was developed for the identification of ceftiofur resistance genes (blaCMY-2, blaTEM-1, and ampC) in swine bacterial pathogens. Using this method, the ceftiofur resistant (n=76) and susceptible (n=45) strains of Bordetella bronchiseptica, Salmonella spp., Escherichia coli, and Pasteurella multocida were screened for the presence of these three genes. The resistant genes were detected in 70% (blaTEM-1), 68% (blaCMY-2) and 45% (ampC) of the resistant isolates and in 18% (blaTEM-1), 27% (blaCMY-2), and 36% (ampC) of the susceptible isolates. Results obtained in the present study showed widespread distribution of these three resistance genes in ceftiofur-resistant swine pathogens. It was also observed that more pathogens are acquiring these resistance genes.

Original languageEnglish (US)
Pages (from-to)139-141
Number of pages3
JournalVeterinary Journal
Volume187
Issue number1
DOIs
StatePublished - Jan 1 2011

Keywords

  • AmpC
  • Bla
  • Bla
  • Ceftiofur
  • β-Lactamase

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