Cherenkov light is created in clinical applications involving high-energy radiation such as in radiation therapy. Due to improvements in camera sensitivity, we are now able to detect and measure Cherenkov light created during radiation therapy using linear accelerators (linacs). However, no method currently exists for using Cherenkov light to estimate the absolute radiation dose delivered to irradiated tissues. We have developed a technique to perform dosimetry with images of Cherenkov emission using deconvolution imaging techniques. The deconvolution technique relies upon the Cherenkov Scatter Function (CSF), a function that describes the scattering of Cherenkov light as it is generated by the treatment photons and propagated through tissue to the surface of the skin. In this study, the CSF was generated through Monte Carlo for 6 MV, 10 MV, and 18 MV photon beams in light, medium, dark skin, and optical tissue phantom materials. Functional dependence of on incident treatment beam angle is shown. The CSFs generated are parameterized using a double-Gaussian distribution and fit coefficients are given. Basic formulation of the deconvolution imaging equation is given to show the relationship of the CSF to X-ray beam flux.
|Original language||English (US)|
|Title of host publication||Optical Interactions with Tissue and Cells XXIX|
|Editors||E. Duco Jansen, Hope Thomas Beier|
|State||Published - 2018|
|Event||Optical Interactions with Tissue and Cells XXIX 2018 - San Francisco, United States|
Duration: Jan 29 2018 → Jan 30 2018
|Name||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Conference||Optical Interactions with Tissue and Cells XXIX 2018|
|Period||1/29/18 → 1/30/18|
Bibliographical noteFunding Information:
The authors would like to thank Dr. Rongxiao Zhang from Harvard University, MA, for his helpful discussion and debugging of simulations. We would also like to thank Dr. Adam Green at the University of St. Thomas, MN, for his insight into optical aspects of the project. The presented work was funded by the University of Minnesota, Department of Radiation Oncology research grant.
© 2018 SPIE.
Copyright 2018 Elsevier B.V., All rights reserved.
- Cherenkov radiation
- Monte Carlo
- radiation dosimetry
- tissue optics