Characterization of the Cherenkov scatter function for use in superficial dose measurement from external beam radiation treatments

Eric Brost; Yoichi Watanabe

doi:10.1117/12.2282869

Characterization of the Cherenkov scatter function for use in superficial dose measurement from external beam radiation treatments

Eric Brost, Yoichi Watanabe

Radiation Oncology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

Cherenkov light is created in clinical applications involving high-energy radiation such as in radiation therapy. Due to improvements in camera sensitivity, we are now able to detect and measure Cherenkov light created during radiation therapy using linear accelerators (linacs). However, no method currently exists for using Cherenkov light to estimate the absolute radiation dose delivered to irradiated tissues. We have developed a technique to perform dosimetry with images of Cherenkov emission using deconvolution imaging techniques. The deconvolution technique relies upon the Cherenkov Scatter Function (CSF), a function that describes the scattering of Cherenkov light as it is generated by the treatment photons and propagated through tissue to the surface of the skin. In this study, the CSF was generated through Monte Carlo for 6 MV, 10 MV, and 18 MV photon beams in light, medium, dark skin, and optical tissue phantom materials. Functional dependence of on incident treatment beam angle is shown. The CSFs generated are parameterized using a double-Gaussian distribution and fit coefficients are given. Basic formulation of the deconvolution imaging equation is given to show the relationship of the CSF to X-ray beam flux.

Original language	English (US)
Title of host publication	Optical Interactions with Tissue and Cells XXIX
Editors	E. Duco Jansen, Hope Thomas Beier
Publisher	SPIE
ISBN (Electronic)	9781510614697
DOIs	https://doi.org/10.1117/12.2282869
State	Published - 2018
Event	Optical Interactions with Tissue and Cells XXIX 2018 - San Francisco, United States Duration: Jan 29 2018 → Jan 30 2018

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10492
ISSN (Print)	1605-7422

Conference

Conference	Optical Interactions with Tissue and Cells XXIX 2018
Country/Territory	United States
City	San Francisco
Period	1/29/18 → 1/30/18

Bibliographical note

Funding Information:
The authors would like to thank Dr. Rongxiao Zhang from Harvard University, MA, for his helpful discussion and debugging of simulations. We would also like to thank Dr. Adam Green at the University of St. Thomas, MN, for his insight into optical aspects of the project. The presented work was funded by the University of Minnesota, Department of Radiation Oncology research grant.

Publisher Copyright:
© 2018 SPIE.

Keywords

Cherenkov radiation
Monte Carlo
radiation dosimetry
tissue optics

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Brost, E., & Watanabe, Y. (2018). Characterization of the Cherenkov scatter function for use in superficial dose measurement from external beam radiation treatments. In E. D. Jansen, & H. T. Beier (Eds.), Optical Interactions with Tissue and Cells XXIX Article 104920M (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10492). SPIE. https://doi.org/10.1117/12.2282869

Characterization of the Cherenkov scatter function for use in superficial dose measurement from external beam radiation treatments. / Brost, Eric; Watanabe, Yoichi.
Optical Interactions with Tissue and Cells XXIX. ed. / E. Duco Jansen; Hope Thomas Beier. SPIE, 2018. 104920M (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10492).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Brost, E & Watanabe, Y 2018, Characterization of the Cherenkov scatter function for use in superficial dose measurement from external beam radiation treatments. in ED Jansen & HT Beier (eds), Optical Interactions with Tissue and Cells XXIX., 104920M, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10492, SPIE, Optical Interactions with Tissue and Cells XXIX 2018, San Francisco, United States, 1/29/18. https://doi.org/10.1117/12.2282869

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abstract = "Cherenkov light is created in clinical applications involving high-energy radiation such as in radiation therapy. Due to improvements in camera sensitivity, we are now able to detect and measure Cherenkov light created during radiation therapy using linear accelerators (linacs). However, no method currently exists for using Cherenkov light to estimate the absolute radiation dose delivered to irradiated tissues. We have developed a technique to perform dosimetry with images of Cherenkov emission using deconvolution imaging techniques. The deconvolution technique relies upon the Cherenkov Scatter Function (CSF), a function that describes the scattering of Cherenkov light as it is generated by the treatment photons and propagated through tissue to the surface of the skin. In this study, the CSF was generated through Monte Carlo for 6 MV, 10 MV, and 18 MV photon beams in light, medium, dark skin, and optical tissue phantom materials. Functional dependence of on incident treatment beam angle is shown. The CSFs generated are parameterized using a double-Gaussian distribution and fit coefficients are given. Basic formulation of the deconvolution imaging equation is given to show the relationship of the CSF to X-ray beam flux.",

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Characterization of the Cherenkov scatter function for use in superficial dose measurement from external beam radiation treatments

Abstract

Publication series

Conference

Bibliographical note

Keywords

Access

OpenUrl availability

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