Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)- ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6] -tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines

Jim J. Xiao, Ying Huang, Zunyan Dai, Wolfgang Sadée, Jiyun Chen, Shujun Liu, Guido Marcucci, John Byrd, Joseph M. Covey, John Wright, Michael Grever, Kenneth K. Chan

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Medicine & Life Sciences