Chromatin Compaction at Hox Loci: A Polycomb Tale beyond Histone Tails

Jeffrey A. Simon

doi:10.1016/j.molcel.2010.04.018

Chromatin Compaction at Hox Loci: A Polycomb Tale beyond Histone Tails

Jeffrey A. Simon

Genetics, Cell Biology and Development (CBS)

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

A new study in this issue of Molecular Cell (Eskeland et al., 2010) implicates Polycomb repressive complex 1 (PRC1) in compacting Hox gene chromatin in mouse embryonic stem cells and suggests that compaction, rather than histone tail ubiquitylation, confers Hox gene silencing.

Original language	English (US)
Pages (from-to)	321-322
Number of pages	2
Journal	Molecular Cell
Volume	38
Issue number	3
DOIs	https://doi.org/10.1016/j.molcel.2010.04.018
State	Published - May 14 2010

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title = "Chromatin Compaction at Hox Loci: A Polycomb Tale beyond Histone Tails",

abstract = "A new study in this issue of Molecular Cell (Eskeland et al., 2010) implicates Polycomb repressive complex 1 (PRC1) in compacting Hox gene chromatin in mouse embryonic stem cells and suggests that compaction, rather than histone tail ubiquitylation, confers Hox gene silencing.",

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AB - A new study in this issue of Molecular Cell (Eskeland et al., 2010) implicates Polycomb repressive complex 1 (PRC1) in compacting Hox gene chromatin in mouse embryonic stem cells and suggests that compaction, rather than histone tail ubiquitylation, confers Hox gene silencing.

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Chromatin Compaction at Hox Loci: A Polycomb Tale beyond Histone Tails

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