Chronic cavitary histoplasmosis. Failure of oral treatment with ketoconazole

C. A. Quinones; A. G. Reuben; R. J. Hamill; D. M. Musher; A. B. Gorin; G. A. Sarosi

doi:10.1378/chest.95.4.914

Chronic cavitary histoplasmosis. Failure of oral treatment with ketoconazole

C. A. Quinones, A. G. Reuben, R. J. Hamill, D. M. Musher, A. B. Gorin, G. A. Sarosi

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Abstract

Ketoconazole appears to be a safe drug in the treatment of chronic cavitary histoplasmosis. Primary failure and relapse have been described, requiring amphotericin B, even after long therapy with ketoconazole. Four typical cases are presented. We caution about such potential failures and stress the importance of close observation of patients begun on therapy with ketoconazole for chronic cavitary histoplasmosis.

Original language	English (US)
Pages (from-to)	914-916
Number of pages	3
Journal	CHEST
Volume	95
Issue number	4
DOIs	https://doi.org/10.1378/chest.95.4.914
State	Published - 1989
Externally published	Yes

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title = "Chronic cavitary histoplasmosis. Failure of oral treatment with ketoconazole",

abstract = "Ketoconazole appears to be a safe drug in the treatment of chronic cavitary histoplasmosis. Primary failure and relapse have been described, requiring amphotericin B, even after long therapy with ketoconazole. Four typical cases are presented. We caution about such potential failures and stress the importance of close observation of patients begun on therapy with ketoconazole for chronic cavitary histoplasmosis.",

author = "Quinones, {C. A.} and Reuben, {A. G.} and Hamill, {R. J.} and Musher, {D. M.} and Gorin, {A. B.} and Sarosi, {G. A.}",

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AU - Quinones, C. A.

AU - Reuben, A. G.

AU - Hamill, R. J.

AU - Musher, D. M.

AU - Gorin, A. B.

AU - Sarosi, G. A.

PY - 1989

Y1 - 1989

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AB - Ketoconazole appears to be a safe drug in the treatment of chronic cavitary histoplasmosis. Primary failure and relapse have been described, requiring amphotericin B, even after long therapy with ketoconazole. Four typical cases are presented. We caution about such potential failures and stress the importance of close observation of patients begun on therapy with ketoconazole for chronic cavitary histoplasmosis.

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Chronic cavitary histoplasmosis. Failure of oral treatment with ketoconazole

Abstract

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