CI‐911: A placebo‐controlled study in patients with primary degenerative dementia

Maurice W. Dysken; Susan Anton‐Johnson; Linda Klein; Michael Kuskowski; Lawrence J. Schut; Steven H. Miles; Gabe J. Maletta; Richard De Jong

doi:10.1002/ddr.430120309

CI‐911: A placebo‐controlled study in patients with primary degenerative dementia

Maurice W. Dysken, Susan Anton‐Johnson, Linda Klein, Michael Kuskowski, Lawrence J. Schut, Steven H. Miles, Gabe J. Maletta, Richard De Jong

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Abstract

Twenty patients with primary degenerative dementia participated in a 6‐week, doseranging, double‐blind, placebo‐controlled study of Cl‐911, a cognition activator that enhances performance in animal models of impaired cognition. Cl‐911 was well tolerated in these patients, but it did not result in significant improvement on objective measures of cognition, social functioning, or self‐care.

Original language	English (US)
Pages (from-to)	267-270
Number of pages	4
Journal	Drug Development Research
Volume	12
Issue number	3-4
DOIs	https://doi.org/10.1002/ddr.430120309
State	Published - 1988
Externally published	Yes

Keywords

Alzheimer's disease
clinical trial
nootropic

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title = "CI‐911: A placebo‐controlled study in patients with primary degenerative dementia",

abstract = "Twenty patients with primary degenerative dementia participated in a 6‐week, doseranging, double‐blind, placebo‐controlled study of Cl‐911, a cognition activator that enhances performance in animal models of impaired cognition. Cl‐911 was well tolerated in these patients, but it did not result in significant improvement on objective measures of cognition, social functioning, or self‐care.",

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T2 - A placebo‐controlled study in patients with primary degenerative dementia

AU - Dysken, Maurice W.

AU - Anton‐Johnson, Susan

AU - Klein, Linda

AU - Kuskowski, Michael

AU - Schut, Lawrence J.

AU - Miles, Steven H.

AU - Maletta, Gabe J.

AU - De Jong, Richard

PY - 1988

Y1 - 1988

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AB - Twenty patients with primary degenerative dementia participated in a 6‐week, doseranging, double‐blind, placebo‐controlled study of Cl‐911, a cognition activator that enhances performance in animal models of impaired cognition. Cl‐911 was well tolerated in these patients, but it did not result in significant improvement on objective measures of cognition, social functioning, or self‐care.

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KW - clinical trial

KW - nootropic

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IS - 3-4

ER -

CI‐911: A placebo‐controlled study in patients with primary degenerative dementia

Abstract

Keywords

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