Abstract
Atomoxetine is a nonstimulant medication used to treat attention-deficit/hyperactivity disorder (ADHD). Cytochrome P450 (CYP)2D6 polymorphisms influence the metabolism of atomoxetine thereby affecting drug efficacy and safety. We summarize evidence from the published literature supporting these associations and provide therapeutic recommendations for atomoxetine based on CYP2D6 genotype (updates at www.cpicpgx.org).
Original language | English (US) |
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Pages (from-to) | 94-102 |
Number of pages | 9 |
Journal | Clinical pharmacology and therapeutics |
Volume | 106 |
Issue number | 1 |
DOIs | |
State | Published - Jul 2019 |
Bibliographical note
Publisher Copyright:© 2019 The Authors Clinical Pharmacology & Therapeutics © 2019 American Society for Clinical Pharmacology and Therapeutics