Clinical, radiographic, histologic, and histomorphometric comparison of pepgen p-15 particulate and pepgen p-15 flow in extraction sockets: A same-mouth case study

Jack Hahn, Michael D. Rohrer, Andrew J. Tofe

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Purpose Although the efficacy of PepGen P-15 particulate has been conclusively demonstrated in two multicenter clinical studies, the effect of a new hydrogel formulation containing PepGen P-15 on bone repair has not been previously demonstrated. Materials and Methods PepGen P-15 Flow contains PepGen P-15 particulate in a biocompatible hydrogel, which provides spacing between the particles. In this case study, bone repair of both PepGen P-15 particles and PepGen P-15 Flow was compared to natural bone in same-mouth extraction sockets. Results The radiographic, histologic, and histomorphometric evaluations showed enhanced bone formation and faster particle resorption with PepGen P-15 Flow compared to the PepGen P-15 particulate. Conclusion The accelerated bone formation by PepGen P-15 Flow may provide faster implant placement.

Original languageEnglish (US)
Pages (from-to)170-174
Number of pages5
JournalImplant Dentistry
Volume12
Issue number2
DOIs
StatePublished - Jan 1 2003

Keywords

  • Anorganic bone mineral
  • Enhanced bone regeneration
  • Hydrogel

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