Coarsening nature of liquid-ordered domain in model membrane

Jeng Hun Suh, Sang Wook Lee, Yong Sang Ryu, Youngjoo Sohn, Sin Doo Lee

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


We present the coarsening dynamics of a liquid-ordered (Lo) domain in a supported lipid membrane under an electric field. In a relatively small nanosmooth region surrounded by geometrical walls of nanocorrugated regions, full coarsening of the Lo domain was produced while in a large nanosmooth region, an intermediate, less-ordered Lo domain was developed so that the diffusion of charged phospholipids in the liquid-disordered (Ld) domain was allowed across the geometrical walls in the presence of an electric field. No appreciable diffusion of the charged lipids into a fully coarsened Lo domain by the electric field implies that the structural ordering of the membrane components plays a significant role on the formation of lipid rafts for biological processes.

Original languageEnglish (US)
Pages (from-to)81-87
Number of pages7
JournalMolecular crystals and liquid crystals
Issue number1
StatePublished - Sep 2 2014

Bibliographical note

Funding Information:
This work was supported in part by Samsung Display Company, Korea.

Publisher Copyright:
Copyright © Taylor & Francis Group, LLC.

Copyright 2015 Elsevier B.V., All rights reserved.


  • Charged lipids
  • Coarsening dynamics
  • Lipid raft
  • Liquidordered
  • Supported lipid membrane

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