Veng-Pedersen and Modi have begun some very interesting investigations. The neural net technique as applied to pharmacodynamics appears to be a promising area of research. However, the results are far from conclusive at present. I believe it is too early to state that the neural net techniques will supplant the more traditional modeling techniques, particularly for short-term goals. Moreover, I hope that the former do not completely replace the latter, as the latter are what ultimately lead to the insights which are the main event in scientific discovery and progress.