TY - JOUR
T1 - Comparison of pain scores with 30-gauge and 32-gauge needles for periocular botulinum toxin type A injections
AU - Yomtoob, David E.
AU - Dewan, Mohit A.
AU - Lee, Michael S.
AU - Harrison, Andrew R.
PY - 2009/9
Y1 - 2009/9
N2 - PURPOSE: To determine whether a 32-gauge needle can reduce the pain associated with periocular injections of botulinum toxin type A compared with 30-gauge needles. METHODS: In this prospective, randomized, masked study, 30 patients received bilateral periocular injections of botulinum toxin type A for benign essential blepharospasm. For each patient, a 30-gauge needle was used on one side of the face, and a 32-gauge needle was used on the other side. Equal number of injections and equal amounts of botulinum toxin type A at each injection site were administered on each side of the face. Patients were then asked to rate their pain level on each side of the face, using a standardized 11-point visual analogue pain scale. RESULTS: The average pain score was 4.38 ± 2.02 for 30-gauge needles and 3.98 ± 1.65 for 32-gauge needles. Statistical analysis via Mann-Whitney U test confirmed the null hypothesis that no statistical difference in pain level existed between the 2 needle sizes. CONCLUSIONS: There is no difference in perceived pain when comparing periocular botulinum toxin type A injections with 30- and 32-gauge needles. In addition, smaller gauge needles require special order and result in greater cost. The authors recommend continued use of 30-gauge needles for botulinum toxin injection in the office setting.
AB - PURPOSE: To determine whether a 32-gauge needle can reduce the pain associated with periocular injections of botulinum toxin type A compared with 30-gauge needles. METHODS: In this prospective, randomized, masked study, 30 patients received bilateral periocular injections of botulinum toxin type A for benign essential blepharospasm. For each patient, a 30-gauge needle was used on one side of the face, and a 32-gauge needle was used on the other side. Equal number of injections and equal amounts of botulinum toxin type A at each injection site were administered on each side of the face. Patients were then asked to rate their pain level on each side of the face, using a standardized 11-point visual analogue pain scale. RESULTS: The average pain score was 4.38 ± 2.02 for 30-gauge needles and 3.98 ± 1.65 for 32-gauge needles. Statistical analysis via Mann-Whitney U test confirmed the null hypothesis that no statistical difference in pain level existed between the 2 needle sizes. CONCLUSIONS: There is no difference in perceived pain when comparing periocular botulinum toxin type A injections with 30- and 32-gauge needles. In addition, smaller gauge needles require special order and result in greater cost. The authors recommend continued use of 30-gauge needles for botulinum toxin injection in the office setting.
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U2 - 10.1097/IOP.0b013e3181b1e526
DO - 10.1097/IOP.0b013e3181b1e526
M3 - Article
C2 - 19966651
AN - SCOPUS:70349730239
SN - 0740-9303
VL - 25
SP - 376
EP - 377
JO - Ophthalmic plastic and reconstructive surgery
JF - Ophthalmic plastic and reconstructive surgery
IS - 5
ER -