Comparisons of emotional health by diagnosis among women with early stage gynecological cancers

Audrey Messelt; Lauren Thomaier; Patricia I. Jewett; Heewon Lee; Deanna Teoh; Susan A. Everson-Rose; Anne H. Blaes; Rachel I. Vogel

doi:10.1016/j.ygyno.2020.12.019

Comparisons of emotional health by diagnosis among women with early stage gynecological cancers

Audrey Messelt, Lauren Thomaier, Patricia I. Jewett, Heewon Lee, Deanna Teoh, Susan A. Everson-Rose, Anne H. Blaes, Rachel I. Vogel

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Objective: To assess self-reported emotional health in a cohort of women with early stage gynecologic cancers and to explore differences based on primary cancer type. Methods: We analyzed survey data from a cohort study of gynecological cancer patients treated at an academic cancer center. Measures of emotional health included cancer-related quality of life, distress, depression, anxiety, posttraumatic stress disorder (PTSD), and posttraumatic growth. Univariate and multivariate linear regression models examined differences in emotional health measures by primary cancer site. Potential confounders considered for inclusion in the final models were age, stage, education, income, partner status, treatment status, and race. Results: 242 patients with early stage disease completed the survey. Patients with cervical and vaginal/vulvar cancers reported greater cancer-related distress, anxiety and PTSD symptoms. Patients with endometrial cancer reported the lowest posttraumatic growth scores, which remained statistically significant after adjustment for demographic and clinical differences. No significant differences in cancer-related quality of life were observed among individuals with different primary cancer sites Conclusions: These data suggest patients with early-stage gynecologic cancer face different psychosocial sequelae based on primary cancer site, though underlying clinical and sociodemographic factors may play a significant role in this observed relationship. Further research is needed to assess poorer emotional health among individuals with vaginal/vulvar cancers and the lower posttraumatic growth among patients with endometrial cancer as posttraumatic growth is considered a potentially beneficial psychosocial outcome of cancer.

Original language	English (US)
Pages (from-to)	805-810
Number of pages	6
Journal	Gynecologic oncology
Volume	160
Issue number	3
DOIs	https://doi.org/10.1016/j.ygyno.2020.12.019
State	Published - Mar 2021

Bibliographical note

Funding Information:
This research was supported by the Masonic Cancer Center at the University of Minnesota by a National Institutes of Health National Cancer Institute grant ( P30 CA77598 ). Support for the use of REDCap was provided by a National Institutes of Health's National Center for Advancing Translational Sciences grant ( UL1TR002494 ). RIV is supported by a Department of Defense Ovarian Cancer Research Program Ovarian Cancer Academy Early Career Investigator Award ( OC180392 W81XWH-19-1-0013 ).

Funding Information:
This research was supported by the Masonic Cancer Center at the University of Minnesota by a National Institutes of Health National Cancer Institute grant (P30 CA77598). Support for the use of REDCap was provided by a National Institutes of Health's National Center for Advancing Translational Sciences grant (UL1TR002494). RIV is supported by a Department of Defense Ovarian Cancer Research Program Ovarian Cancer Academy Early Career Investigator Award (OC180392 W81XWH-19-1-0013).

Publisher Copyright:
© 2020 Elsevier Inc.

Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.

PubMed: MeSH publication types

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, N.I.H., Extramural

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@article{270324568b2842d3a8debe5f91786b8c,

title = "Comparisons of emotional health by diagnosis among women with early stage gynecological cancers",

abstract = "Objective: To assess self-reported emotional health in a cohort of women with early stage gynecologic cancers and to explore differences based on primary cancer type. Methods: We analyzed survey data from a cohort study of gynecological cancer patients treated at an academic cancer center. Measures of emotional health included cancer-related quality of life, distress, depression, anxiety, posttraumatic stress disorder (PTSD), and posttraumatic growth. Univariate and multivariate linear regression models examined differences in emotional health measures by primary cancer site. Potential confounders considered for inclusion in the final models were age, stage, education, income, partner status, treatment status, and race. Results: 242 patients with early stage disease completed the survey. Patients with cervical and vaginal/vulvar cancers reported greater cancer-related distress, anxiety and PTSD symptoms. Patients with endometrial cancer reported the lowest posttraumatic growth scores, which remained statistically significant after adjustment for demographic and clinical differences. No significant differences in cancer-related quality of life were observed among individuals with different primary cancer sites Conclusions: These data suggest patients with early-stage gynecologic cancer face different psychosocial sequelae based on primary cancer site, though underlying clinical and sociodemographic factors may play a significant role in this observed relationship. Further research is needed to assess poorer emotional health among individuals with vaginal/vulvar cancers and the lower posttraumatic growth among patients with endometrial cancer as posttraumatic growth is considered a potentially beneficial psychosocial outcome of cancer.",

author = "Audrey Messelt and Lauren Thomaier and Jewett, {Patricia I.} and Heewon Lee and Deanna Teoh and Everson-Rose, {Susan A.} and Blaes, {Anne H.} and Vogel, {Rachel I.}",

note = "Funding Information: This research was supported by the Masonic Cancer Center at the University of Minnesota by a National Institutes of Health National Cancer Institute grant ( P30 CA77598 ). Support for the use of REDCap was provided by a National Institutes of Health's National Center for Advancing Translational Sciences grant ( UL1TR002494 ). RIV is supported by a Department of Defense Ovarian Cancer Research Program Ovarian Cancer Academy Early Career Investigator Award ( OC180392 W81XWH-19-1-0013 ). Funding Information: This research was supported by the Masonic Cancer Center at the University of Minnesota by a National Institutes of Health National Cancer Institute grant (P30 CA77598). Support for the use of REDCap was provided by a National Institutes of Health's National Center for Advancing Translational Sciences grant (UL1TR002494). RIV is supported by a Department of Defense Ovarian Cancer Research Program Ovarian Cancer Academy Early Career Investigator Award (OC180392 W81XWH-19-1-0013). Publisher Copyright: {\textcopyright} 2020 Elsevier Inc. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",

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AU - Teoh, Deanna

AU - Everson-Rose, Susan A.

AU - Blaes, Anne H.

AU - Vogel, Rachel I.

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N2 - Objective: To assess self-reported emotional health in a cohort of women with early stage gynecologic cancers and to explore differences based on primary cancer type. Methods: We analyzed survey data from a cohort study of gynecological cancer patients treated at an academic cancer center. Measures of emotional health included cancer-related quality of life, distress, depression, anxiety, posttraumatic stress disorder (PTSD), and posttraumatic growth. Univariate and multivariate linear regression models examined differences in emotional health measures by primary cancer site. Potential confounders considered for inclusion in the final models were age, stage, education, income, partner status, treatment status, and race. Results: 242 patients with early stage disease completed the survey. Patients with cervical and vaginal/vulvar cancers reported greater cancer-related distress, anxiety and PTSD symptoms. Patients with endometrial cancer reported the lowest posttraumatic growth scores, which remained statistically significant after adjustment for demographic and clinical differences. No significant differences in cancer-related quality of life were observed among individuals with different primary cancer sites Conclusions: These data suggest patients with early-stage gynecologic cancer face different psychosocial sequelae based on primary cancer site, though underlying clinical and sociodemographic factors may play a significant role in this observed relationship. Further research is needed to assess poorer emotional health among individuals with vaginal/vulvar cancers and the lower posttraumatic growth among patients with endometrial cancer as posttraumatic growth is considered a potentially beneficial psychosocial outcome of cancer.

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Comparisons of emotional health by diagnosis among women with early stage gynecological cancers

Abstract

Bibliographical note

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