Composite Tissue Preservation

Ryan M. Dickey, Austin S. Hembd, Seth Fruge, Nicholas T. Haddock, Klearchos K Papas, Thomas M. Suszynski

Research output: Contribution to journalArticlepeer-review


Composite tissue (CT) preservation is important to outcomes after replant or transplant. Since the first limb replant, the mainstay of preservation has been static cold storage with the amputated part being placed in moistened gauze over ice. Historically, the gold-standard in solid organ preservation has been static cold storage with specialized solution, but this has recently evolved in the last few decades to develop technologies such as machine perfusion and even persufflation. This review explores the impact of cooling and oxygenation on CT, summarizes the work done in the area of CT preservation, discusses lessons learned from our experience in solid organ preservation, and proposes future directions.

Original languageEnglish (US)
Pages (from-to)711-716
Number of pages6
JournalAnnals of plastic surgery
Issue number6
StatePublished - Jun 1 2020
Externally publishedYes

Bibliographical note

Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.


  • composite tissue transplant
  • replant
  • tissue preservation

PubMed: MeSH publication types

  • Journal Article
  • Review


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