Composition or Context: Using Transportability to Understand Drivers of Site Differences in a Large-scale Housing Experiment

Kara E. Rudolph, Nicole M. Schmidt, M. Maria Glymour, Rebecca Crowder, Jessica Galin, Jennifer Ahern, Theresa L. Osypuk

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Background: The Moving To Opportunity (MTO) experiment manipulated neighborhood context by randomly assigning housing vouchers to volunteers living in public housing to use to move to lower poverty neighborhoods in five US cities. This random assignment overcomes confounding limitations that challenge other neighborhood studies. However, differences in MTO's effects across the five cities have been largely ignored. Such differences could be due to population composition (e.g., differences in the racial/ethnic distribution) or to context (e.g., differences in the economy). Methods: Using a nonparametric omnibus test and a multiply robust, semiparametric estimator for transportability, we assessed the extent to which differences in individual-level compositional characteristics that may act as effect modifiers can account for differences in MTO's effects across sites. We examined MTO's effects on marijuana use, behavioral problems, major depressive disorder, and generalized anxiety disorder among black and Latino adolescent males, where housing voucher receipt was harmful for health in some sites but beneficial in others. Results: Comparing point estimates, differences in composition partially explained site differences in MTO effects on marijuana use and behavioral problems but did not explain site differences for major depressive disorder or generalized anxiety disorder. Conclusions: Our findings provide quantitative, rigorous evidence for the importance of context or unmeasured individual-level compositional variables in modifying MTO's effects.

Original languageEnglish (US)
Pages (from-to)199-206
Number of pages8
JournalEpidemiology
Volume29
Issue number2
DOIs
StatePublished - Mar 1 2018

Bibliographical note

Funding Information:
Submitted February 8, 2017; accepted October 18, 2017. From the aSchool of Public Health, University of California, Berkeley, CA; bDepartment of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN; and cDepartment of Epidemiology and Biostatistics, University of California, San Fran-cisco, CA. This work was supported in part by the National Institute on Drug Abuse (K99DA042127-01; PI: Rudolph). T.L.O., M.M.G., and N.M.S. were sup-ported by R01 MD006064. Data and analysis code: Researchers may apply for data access through ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/31661. Computing code required to replicate the results will be made available on the first author’s github page: https://github.com/cherrygarcia/MTO-site-transport-ability-paper-code/blob/master/submissioncode1.R. Disclosure: The authors report no conflicts of interest. Supplemental digital content is available through direct URL citations in the HTML and PDF versions of this article (www.epidem.com). Correspondence: Kara E. Rudolph, 13B University Hall, School of Public Health, Berkeley, CA 94720. E-mail: kara.rudolph@berkeley.edu Copyright 2017 Wolters Kluwer Health, Inc. All rights reserved. ISSN: 1044-3983/18/2902-0199 DOI: 10.1097/EDE.0000000000000774

Funding Information:
This work was supported in part by the National Institute on Drug Abuse (K99DA042127-01; PI: Rudolph). T.L.O., M.M.G., and N.M.S. were supported by R01 MD006064.

Publisher Copyright:
© 2018 Wolters Kluwer Health, Inc.

Fingerprint

Dive into the research topics of 'Composition or Context: Using Transportability to Understand Drivers of Site Differences in a Large-scale Housing Experiment'. Together they form a unique fingerprint.

Cite this