Concurrent Subcutaneous Panniculitis-like T-Cell Lymphoma and B-Cell Acute Lymphoblastic Leukemia in 2 Pediatric Patients

Geoffrey A. Smith, Anya L. Levinson, Robert T. Galvin, Leah E. Lalor, Timothy McCalmont, Linlin Wang, Michael C. Geis, Karah Odegaard, Meghan Hupp, Sheilagh Maguiness, Lucie M Turcotte, Kelly M. Cordoro, Michelle L. Hermiston

Research output: Contribution to journalArticlepeer-review

Abstract

Subcutaneous panniculitis-like T-cell lymphoma is a cutaneous lymphoma characterized by CD8+T-cell infiltrate in the subcutis that is rare in children. Acute lymphoblastic lymphoma is the most common pediatric malignancy and often presents with fevers and pancytopenia. Herein, we report 2 pediatric patients presenting with subcutaneous panniculitis-like T-cell lymphoma and B-cell acute lymphoblastic lymphoma, distinct hematologic malignancies arising from different lymphoid lineages, with no identifiable germline cancer predisposition.

Original languageEnglish (US)
Article number1921
JournalJournal of pediatric hematology/oncology
DOIs
StateAccepted/In press - 2020

Keywords

  • ALL
  • SPTCL
  • clinical decision making
  • concurrent malignancy
  • immune dysregulation

PubMed: MeSH publication types

  • Journal Article

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