Abstract
The conformation of [1-13C,15N]acetyl-L-carnitine is studied by rotational-echo, double-resonance (REDOR) NMR experiments. The REDOR results show that acetyl-L-carnitine adopts an extended molecular conformation in the solid state for both crystalline and lyophilized samples. These findings are in contrast to various X-ray-determined structures of racemic acetylcarnitine showing folded conformations.
Original language | English (US) |
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Pages (from-to) | 10546-10550 |
Number of pages | 5 |
Journal | Journal of the American Chemical Society |
Volume | 117 |
Issue number | 42 |
DOIs | |
State | Published - 1995 |
Externally published | Yes |