Abstract
The hydroxyapatite (HAp)/gelatin (GEL) nanocomposite was prepared through the coprecipitation and then cross-linked by using glutaraldehyde (GA). From FT-IR measurement the spectral features for amide bands and phosphate bands were severely modified by the cross-linkage and the organic content increased with the degree of cross-linkage. From Transmission Electron Microscopy (TEM) and electron diffraction analyses we could confirm the preferentially directional growth of needle-like HAp particles, which were embedded in GEL by the mineralization. Also we could observe worm-like stria patterns of contrast, which were revealed by the mineralization on the individual GEL fibrils. Moiré images were observed in a highly cross-linked HAp/GEL nanocomposite sample and we think the cross-linkage induced the assembly of unordered individual fibrils along the preferential direction.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3087-3094 |
| Number of pages | 8 |
| Journal | Biomaterials |
| Volume | 24 |
| Issue number | 18 |
| DOIs | |
| State | Published - Aug 2003 |
Bibliographical note
Funding Information:The authors greatly appreciate Dr. Stuart Mckernan for TEM work and thank Mr. Kevin Cummings for DT/TGA measurement. This study was partially supported by MDRCBB and 3M ESPE Dental Products.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
Keywords
- Conformation
- Cross-linkage
- Hydroxyapatite-gelatin nanocomposite
- Moiré's fringe