Connections between growth and the cell cycle

Thomas P. Neufeld, Bruce A. Edgar

Research output: Contribution to journalArticlepeer-review

151 Scopus citations


To maintain a constant size during cellular proliferation, a cell's growth rate must match its rate of division. Factors that govern proliferation must therefore coordinately regulate two distinct processes: the cellular biosynthesis that drives accumulation of mass, and progression through the cell division cycle. Recent work has identified several mechanisms which couple cell division to growth. Different mechanisms are used at different times during development to coordinate growth, cell division, and patterning.

Original languageEnglish (US)
Pages (from-to)784-790
Number of pages7
JournalCurrent Opinion in Cell Biology
Issue number6
StatePublished - Dec 1998


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