Continuous magnetophoretic enrichment of rare tumor cells

D. Nawarathna; P. Kumaresan; Y. Zhang; B. Ferguson; S. H. Oh; K. S. Lam; H. T. Soh

Continuous magnetophoretic enrichment of rare tumor cells

D. Nawarathna, P. Kumaresan, Y. Zhang, B. Ferguson, S. H. Oh, K. S. Lam, H. T. Soh

Electrical and Computer Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We present the Continuous-flow Magnetic Activated Cell Sorter (CMACS) device which is capable of enriching rare magnetic particles with high purity. The microfabricated ferromagnetic strips within the microfluidic channels create high magnetic field gradients, which generate the magnetophoretic separation forces. We report on the effective separation of magnetically labeled Human Lymphoma (Jurkat) cells from non-target cells and compare its performance against commercially available macro-scale systems.

Original language	English (US)
Title of host publication	Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Editors	Jean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
Publisher	Chemical and Biological Microsystems Society
Pages	122-124
Number of pages	3
ISBN (Electronic)	9780979806407
State	Published - 2007
Event	11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France Duration: Oct 7 2007 → Oct 11 2007

Publication series

Name	Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference	11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Country/Territory	France
City	Paris
Period	10/7/07 → 10/11/07

Bibliographical note

Publisher Copyright:
© 2007 CBMS.

Keywords

Magnetic separation
Rare cell sorting

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

OpenUrl availability

Full text

Cite this

Nawarathna, D., Kumaresan, P., Zhang, Y., Ferguson, B., Oh, S. H., Lam, K. S., & Soh, H. T. (2007). Continuous magnetophoretic enrichment of rare tumor cells. In J.-L. Viovy, P. Tabeling, S. Descroix, & L. Malaquin (Eds.), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 (pp. 122-124). (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007). Chemical and Biological Microsystems Society.

Continuous magnetophoretic enrichment of rare tumor cells. / Nawarathna, D.; Kumaresan, P.; Zhang, Y. et al.
Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. ed. / Jean-Louis Viovy; Patrick Tabeling; Stephanie Descroix; Laurent Malaquin. Chemical and Biological Microsystems Society, 2007. p. 122-124 (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Nawarathna, D, Kumaresan, P, Zhang, Y, Ferguson, B, Oh, SH, Lam, KS & Soh, HT 2007, Continuous magnetophoretic enrichment of rare tumor cells. in J-L Viovy, P Tabeling, S Descroix & L Malaquin (eds), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, Chemical and Biological Microsystems Society, pp. 122-124, 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, Paris, France, 10/7/07.

Nawarathna D, Kumaresan P, Zhang Y, Ferguson B, Oh SH, Lam KS et al. Continuous magnetophoretic enrichment of rare tumor cells. In Viovy JL, Tabeling P, Descroix S, Malaquin L, editors, Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. Chemical and Biological Microsystems Society. 2007. p. 122-124. (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007).

Nawarathna, D. ; Kumaresan, P. ; Zhang, Y. et al. / Continuous magnetophoretic enrichment of rare tumor cells. Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. editor / Jean-Louis Viovy ; Patrick Tabeling ; Stephanie Descroix ; Laurent Malaquin. Chemical and Biological Microsystems Society, 2007. pp. 122-124 (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007).

@inproceedings{c61d05340e184e2085e39770f280108c,

title = "Continuous magnetophoretic enrichment of rare tumor cells",

abstract = "We present the Continuous-flow Magnetic Activated Cell Sorter (CMACS) device which is capable of enriching rare magnetic particles with high purity. The microfabricated ferromagnetic strips within the microfluidic channels create high magnetic field gradients, which generate the magnetophoretic separation forces. We report on the effective separation of magnetically labeled Human Lymphoma (Jurkat) cells from non-target cells and compare its performance against commercially available macro-scale systems.",

keywords = "Magnetic separation, Rare cell sorting",

author = "D. Nawarathna and P. Kumaresan and Y. Zhang and B. Ferguson and Oh, {S. H.} and Lam, {K. S.} and Soh, {H. T.}",

note = "Publisher Copyright: {\textcopyright} 2007 CBMS.; 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 ; Conference date: 07-10-2007 Through 11-10-2007",

year = "2007",

language = "English (US)",

series = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",

publisher = "Chemical and Biological Microsystems Society",

pages = "122--124",

editor = "Jean-Louis Viovy and Patrick Tabeling and Stephanie Descroix and Laurent Malaquin",

booktitle = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",

}

TY - GEN

T1 - Continuous magnetophoretic enrichment of rare tumor cells

AU - Nawarathna, D.

AU - Kumaresan, P.

AU - Zhang, Y.

AU - Ferguson, B.

AU - Oh, S. H.

AU - Lam, K. S.

AU - Soh, H. T.

PY - 2007

Y1 - 2007

N2 - We present the Continuous-flow Magnetic Activated Cell Sorter (CMACS) device which is capable of enriching rare magnetic particles with high purity. The microfabricated ferromagnetic strips within the microfluidic channels create high magnetic field gradients, which generate the magnetophoretic separation forces. We report on the effective separation of magnetically labeled Human Lymphoma (Jurkat) cells from non-target cells and compare its performance against commercially available macro-scale systems.

AB - We present the Continuous-flow Magnetic Activated Cell Sorter (CMACS) device which is capable of enriching rare magnetic particles with high purity. The microfabricated ferromagnetic strips within the microfluidic channels create high magnetic field gradients, which generate the magnetophoretic separation forces. We report on the effective separation of magnetically labeled Human Lymphoma (Jurkat) cells from non-target cells and compare its performance against commercially available macro-scale systems.

KW - Magnetic separation

KW - Rare cell sorting

UR - http://www.scopus.com/inward/record.url?scp=85088682606&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85088682606&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:85088682606

T3 - Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

SP - 122

EP - 124

BT - Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

A2 - Viovy, Jean-Louis

A2 - Tabeling, Patrick

A2 - Descroix, Stephanie

A2 - Malaquin, Laurent

PB - Chemical and Biological Microsystems Society

T2 - 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Y2 - 7 October 2007 through 11 October 2007

ER -

Continuous magnetophoretic enrichment of rare tumor cells

Abstract

Publication series

Conference

Bibliographical note

Keywords

UN SDGs

OpenUrl availability

Other files and links

Fingerprint

Cite this